G Protein-Coupled Receptors
Welcome to the G Protein-Coupled Receptor Main Page of the
Molecular Recognition Section.
Although our section is mainly involved in investigating the Molecular
Recognition process between
and their ligands, we are interested in all aspects of Molecular Recognition.
Since all currently known
P1 purinoceptor subtypes,
P2 purinoceptor subtypes
are members of the protein family commonly known as G Protein-Coupled
Receptors (GPCRs), we have collected a fair amount of data on GPCRs.
These data are organized in three sections:
The coordinates of our
A2A adenosine receptor model
(1MMH), and our
P2Y1 receptor model
(1DDD) are available from the
Protein Data Bank.
The current release of the
GPCR mutant database
is version 3.2.1.
There is an informal network of groups trying to work out
an international standard for GPCR database formats.
The institutes participating in this effort are:
our section at NIH
GCRdB at Harvard
GPCRDB at EMBL
GRAP at the
University of Tromsø
Olfactory Receptor Database at Yale
Since this is a very dynamic field with lots of opportunities, we highly value
your opinion of the current servers, what changes you would like to see made,
or what new services you would like to see implemented.
Please drop us a note (e-mail or snail mail) at the address below.
Also, please read our